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Antisense Oligonucleotide Targeting Fibroblast Growth Factor Receptor-1 Stimulates Cellular Activity of Hair Follicles in an In Vitro Organ Culture System

research Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)-1 stimulates cellular activity of hair follicles in anin vitroorgan culture system

7 citations , March 2007 in “International Journal of Dermatology”

Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.

research Signaling modality within gp130 receptor enhances tissue regeneration

January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.

research P085 Therapeutic effects of growth factor cocktail including FGF9 scalp application in patients with androgenetic alopecia

January 2016 in “프로그램북(구 초록집)”

The growth factor cocktail with FGF9 significantly increased hair density and diameter in patients with androgenetic alopecia.

research Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets.

6 citations , April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

research RAPID ALKALINIZATION FACTOR 22 is a key modulator of the root hair growth responses to fungal ethylene emissions in Arabidopsis

7 citations , September 2024 in “PLANT PHYSIOLOGY”

RALF22 is essential for root hair growth in response to fungal emissions in Arabidopsis.

research Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells

July 2017

IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.

research Faculty Opinions recommendation of GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells.

January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GDNF helps grow hair and heal skin wounds by acting on specific stem cells.

research Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.

107 citations , June 1997 in “PubMed”

EGFR is essential for normal hair development and follicle differentiation.

research VEGF165 induces differentiation of hair follicle stem cells into endothelial cells and plays a role in in vivo angiogenesis

36 citations , February 2017 in “Journal of Cellular and Molecular Medicine”

VEGF165 helps hair follicle stem cells become blood vessel cells, aiding new blood vessel growth.

research Mutations in the Serum/Glucocorticoid Regulated Kinase 3 (Sgk3) Are Responsible for the Mouse Fuzzy (fz) Hair Phenotype

11 citations , October 2007 in “Journal of Investigative Dermatology”

Mutations in the Sgk3 gene cause fuzzy hair in mice.

research Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway

36 citations , April 2016 in “Biochimie”

A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.

research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression

3 citations , June 2021 in “Frontiers in genetics”

The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.

Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process

research Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process

27 citations , February 2017 in “Clinical, Cosmetic and Investigational Dermatology”

New compounds were found to help increase hair growth and decrease hair loss.

research IGFBP5 Promotes Neuronal Apoptosis in a 6-OHDA-Toxicant Model of Parkinson’s Disease by Inhibiting the Sonic Hedgehog Signaling Pathway

8 citations , January 2024 in “Medical Principles and Practice”

IGFBP5 may be a potential target for Parkinson's treatment by reducing neuron death.

research Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling*

25 citations , August 2010 in “Journal of Biological Chemistry”

Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.

research GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis

24 citations , December 2013 in “Archives of Dermatological Research”

research Epidermal growth factor precursor retards hair growth cycle in vivo

January 2001

research The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice

January 2026 in “PLoS Biology”

ARHGEF3 is essential for proper hair follicle development in mice.

research Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors

56 citations , February 2013 in “International Journal of Molecular Medicine”

Growth factors help hair follicle stem cells grow and stay versatile.

research Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development

25 citations , September 2018 in “Molecular Biology of the Cell”

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

research Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle

55 citations , September 2003 in “Experimental Dermatology”

PDGF signaling may play a role in hair growth cycle regulation.

research Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle

94 citations , July 2003 in “Journal of biological chemistry/The Journal of biological chemistry”

EGF controls hair growth by regulating hair follicles' growth phases.

research 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration

June 2020 in “Journal of Investigative Dermatology”

Tiny particles from skin cells can help activate hair growth.

research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

84 citations , October 2014 in “PLoS Genetics”

Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.

research EGFR: stopping stathmin to start the cycle

March 2016 in “Experimental Dermatology”

EGFR helps hair follicles transition properly by controlling Stathmin levels.

research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis

91 citations , June 2011 in “The EMBO Journal”

TCF/Lef1 activity is essential for proper skin cell development and renewal.

research Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice

32 citations , January 2010 in “Journal of Dermatological Science”

Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.

research VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway

23 citations , June 2012 in “Molecular Biology Reports”

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

research Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles

20 citations , December 2013 in “PTR. Phytotherapy research/Phytotherapy research”

Ginsenoside Rg3 may help hair growth by increasing a growth-related protein in hair cells.

research Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes

11 citations , October 2018 in “Nucleic Acid Therapeutics”

Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.

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