research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
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research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research A Human Folliculoid Microsphere Assay for Exploring Epithelial– Mesenchymal Interactions in the Human Hair Follicle
HFMs can help study hair growth and test potential hair growth drugs.
research The control of hair growth: An overview
Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
research Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic
Different skin cells produce unique materials, which can improve skin substitutes for healing.
research Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges
Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.
research Shikimic acid, a mannose bioisostere, promotes hair growth with the induction of anagen hair cycle
Shikimic acid promotes hair growth.
research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Multifaceted role of hair follicle dermal cells in bioengineered skins
Human hair follicle dermal cells can effectively replace other cells in engineered skin.
research Advanced therapies of skin injuries
New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research Profibrotic Subsets of SPP1+ Macrophages and POSTN+ Fibroblasts Contribute to Fibrotic Scarring in Acne Keloidalis
Corticosteroids can reduce scarring in acne keloidalis by targeting specific cells.
research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury
High-dose radiation speeds up aging in skin stem cells.
research 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing
A 3D cell model can rejuvenate stem cells to improve wound healing.
research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects
3D spheroid culture makes stem cells better at reducing inflammation.
research Expression and functional relevance of melatonin receptors in hair follicle biology
Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
research Flightless I Expression Enhances Murine Claw Regeneration Following Digit Amputation
Mice with more Flightless I protein grew back their claws better after amputation.
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research The origins of skin diversity: lessons from dermal fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research Repigmentation of Gray Hair After Thyroid Hormone Treatment
Gray hair regained color after thyroid hormone treatment.
research “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds
The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
research Dermal papilla regulation of hair growth and pigmentation
Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
research Hair Follicle Reconstruction and Stem Cells
Stem cells could improve hair growth and new treatments for baldness are being researched.
research Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation
MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
research Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes
Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
research THBS4 promotes hair regeneration by inducing dermal mechanical niche adaptation
THBS4 helps hair grow by activating hair follicle stem cells.
research Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging
The α-MSH-MC1R-cAMP pathway does not protect skin cells from UVA damage.
research Comparative analysis of stemness between dermal papilla cells and human dermalstem/progenitor cells
Human dermal stem/progenitor cells can divide and differentiate more than hair follicle dermal papilla cells.