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Did you mean Fibroblast Growth Factor Receptor 2?

GlossaryFibroblast Growth Factor Receptor 2

protein involved in cell growth and tissue repair

Fibroblast Growth Factor Receptor 2 (FGFR2) is a protein that plays a crucial role in cell growth, differentiation, and tissue repair. It is particularly important in the development of bones and skin, and mutations in the FGFR2 gene can lead to various developmental disorders and contribute to conditions like craniosynostosis and certain cancers.

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research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction

119 citations , November 2014 in “Trends in Cell Biology”

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells

66 citations , February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

research Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells”

June 2007 in “Journal of Investigative Dermatology”

research Signaling by the Platelet-Derived Growth Factor Receptor Family

January 2009

PDGF signaling is crucial for cell development, wound healing, and fluid regulation in the body.

Transforming Growth Factor-β Signaling-Mediated Wound Healing Is Required for Hair Follicle Neogenesis

research 484 Transforming growth factor-β signaling-mediated wound healing is required hair follicle neogenesis

November 2024 in “Journal of Investigative Dermatology”

TGF-β signaling is essential for new hair growth after wounds.

research Platycladus orientalis Leaf Extract Promotes Hair Growth via Non-Receptor Tyrosine Kinase ACK1 Activation

October 2024 in “Current Issues in Molecular Biology”

Platycladus orientalis leaf extract helps hair grow by activating certain proteins.

Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

research Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

16 citations , February 2007 in “Plastic and Reconstructive Surgery”

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

Beta-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding

research β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED]

13 citations , February 2018 in “Plastic and Reconstructive Surgery”

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations , February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

research Effects of oleanolic acid on hair growth in mouse dorsal skin mediated via regulation of inflammatory cytokines

March 2023 in “Journal of Applied Biomedicine”

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

research FGF18 signaling determines radioresistance of telogen hair follicles by the arrest of hair cycling

September 2016 in “Journal of dermatological science”

FGF18 helps hair follicles resist radiation by stopping hair growth cycles.

research FGF signaling for hair cycle resting phase alleviates radiation alopecia

1 citations , September 2016 in “Journal of Dermatological Science”

FGF18 treatment during hair's resting phase can protect against hair loss from radiation.

research Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications

January 2026 in “Current Issues in Molecular Biology”

FGF-7 helps hair grow by activating hair follicles and is a promising target for hair loss treatments.

research Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin

7 citations , March 2022 in “International Journal of Molecular Sciences”

FGF21 can help reduce skin inflammation caused by C. acnes.

research A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control

2 citations , September 2004 in “Experimental Dermatology”

VR1 signaling can inhibit hair growth by affecting cell processes and increasing hair growth inhibitors.

Cellular and Molecular Characterization of Sebaceous Gland Self-Renewal and Regeneration Following Complete Genetic Ablation

research 1405 Cellular and molecular characterization of sebaceous gland self-renewal and regeneration following complete genetic ablation

April 2023 in “Journal of Investigative Dermatology”

The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.

Comparative Transcriptome Profiling of Hair Follicles from Forest Musk Deer at Different Stages

research Comparative transcriptome profiling of hair follicles from forest musk deer (Moschus berezovskii) at different stages

November 2022 in “Research Square (Research Square)”

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

research Comparative genome analyses reveal the unique genetic composition and selection signals underlying the phenotypic characteristics of three Chinese domestic goat breeds

30 citations , November 2019 in “Genetics selection evolution”

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

research Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations , May 2018 in “Frontiers in physiology”

Certain RNA molecules are important for the development of wool follicles in sheep.

research Review of Women with Vision: The Presentation Sisters of South Dakota, 1880-1985

January 1990

Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.

research GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE

90 citations , October 1996 in “Dermatologic Clinics”

Growth factors are crucial for hair development and could help treat hair diseases.

GDNF Neurotrophic Factor Signaling Determines the Fate of Dermal Fibroblasts in Wound-Induced Hair Neogenesis and Skin Regeneration

research GDNF neurotrophic factor signaling determines the fate of dermal fibroblasts in wound‐induced hair neogenesis and skin regeneration

2 citations , January 2022 in “Experimental Dermatology”

GDNF signaling helps in hair growth and skin healing after a wound.

research Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo

4 citations , December 2022 in “Cells”

Engineered nanovesicles from fibroblasts may help treat hair loss by promoting hair growth.

research 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line

April 2019 in “Journal of Investigative Dermatology”

Y27632 increases cell growth through EGFR signaling, not ROCK1/2.

research 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration

June 2020 in “Journal of Investigative Dermatology”

Tiny particles from skin cells can help activate hair growth.