92 citations
,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
154 citations
,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
58 citations
,
November 2012 in “PLoS ONE” Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
54 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
50 citations
,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
49 citations
,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
46 citations
,
December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
14 citations
,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
9 citations
,
January 2023 in “International Journal of Biological Sciences” CTHRC1 is essential for healing and preventing heart rupture after a heart attack.
8 citations
,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
7 citations
,
April 2014 in “Cell biology international” Melatonin treatment helps improve skin health in postmenopausal rats.
5 citations
,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
5 citations
,
February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
5 citations
,
June 2023 in “BMC genomics” A specific gene mutation causes long hair in Angora rabbits.
2 citations
,
May 2023 in “Marine Drugs” Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
1 citations
,
November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” The Enriched-GF method efficiently produces high-yield growth factors for tissue repair.
March 2026 in “Wound Repair and Regeneration” MARCKSL1 is important for wound healing and could be a target to reduce scarring.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
Lack of certain cells causes abnormal nipple development and nursing failure.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
July 2023 in “International journal of trichology” Cellcurin therapy with microneedling increases hair density and thickness in treating hair loss in men and women.
June 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.
133 citations
,
February 2019 in “PLoS Biology” Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
29 citations
,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.