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Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins

research 1322 Molecular profiling of frontal fibrosing alopecia (FFA) reveals TH1 and JAK-STAT up-regulation with no suppression of hair keratins

2 citations , April 2018 in “Journal of Investigative Dermatology”

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

research Dwarf planet Ceres and the ingredients of life

2 citations , February 2017 in “Science”

The Dawn spacecraft found that Ceres has complex organic molecules and a lot of water ice, hinting it might support life.

research Whole Tooth Regenerative Therapy Using a Bioengineered Tooth Germ

2 citations , December 2013 in “Current Oral Health Reports”

Bioengineered teeth could replace damaged teeth and restore oral functions.

research Chemotherapy-Induced Alopecia

2 citations , January 2012 in “InTech eBooks”

Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.

Tissue Homeostasis and Regeneration: Human Limitations and Potential

research Tissue homeostasis

2 citations , January 2008 in “Elsevier eBooks”

Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.

research Recent advances in glycopeptide hydrogels: design, biological functions, and biomedical applications

1 citations , June 2025 in “Frontiers in Bioengineering and Biotechnology”

Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.

Intraoperative Bioprinting of Human Adipose-Derived Stem Cells and Extracellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation During Full-Thickness Craniomaxillofacial Skin Reconstruction

research Intraoperative Bioprinting of Human Adipose-derived Stem cells and Extra-cellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation during Full-thickness Craniomaxillofacial Skin Reconstruction

1 citations , October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

research Characterization of Primary Cilia and Intraflagellar Transport 20 in the Epidermis

1 citations , January 2020

Ift20 is essential for hair follicle function and skin cell movement.

A Discrete Transition Zone Between Cuticle and Cortex Layers of a Human Hair Fiber: Changes Observed in the Presence of Breast Cancer

research A discrete transition zone between cuticle and cortex layers of a human hair fibre: changes observed in the presence of breast cancer

1 citations , October 2017 in “ecancermedicalscience”

Breast cancer alters specific molecular structures in hair, which revert after cancer removal.

research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

1 citations , May 2017 in “InTech eBooks”

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

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