Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
April 2019 in “Journal of Investigative Dermatology” Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.
221 citations
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July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” BMAL1 controls skin cell growth and UV damage risk, peaking at night.
130 citations
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August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
119 citations
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July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
77 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research ACNE
58 citations
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January 1997 in “Dermatologic Clinics” Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
56 citations
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November 2003 in “Journal of Investigative Dermatology” MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
45 citations
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August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
33 citations
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March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
31 citations
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January 2011 in “Dermato-endocrinology” Melatonin protects skin against UV damage by regulating various cellular processes.
31 citations
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April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
30 citations
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July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
29 citations
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June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
27 citations
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July 2018 in “Experimental dermatology” Autophagy is crucial for normal sebaceous gland function and sebum composition.
26 citations
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May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
22 citations
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March 2012 in “Molecular Medicine Reports” DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
21 citations
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November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
21 citations
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November 2020 in “Chemical Engineering Journal” The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
20 citations
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
18 citations
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January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
18 citations
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September 1990 in “Veterinary Dermatology” Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.
13 citations
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March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
11 citations
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September 2012 in “Journal of Nanjing Medical University” Cyclosporine A was found to increase hair growth in mouse whisker follicles.
10 citations
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May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
10 citations
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December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
8 citations
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January 2013 in “BioMed Research International” Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
7 citations
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March 2021 in “Biology” Scaffold improves hair growth potential.