research Repurposing Metformin for Dermatological Use: Mechanisms, Evidence, and Clinical Perspectives
Metformin shows promise for treating skin conditions, but more research is needed.
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450-480 / 1000+ results research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Botulinum Toxin Type A for Preventing Facial Trauma and Hypertrophic Scars: A Meta‐Analysis and Trial Sequential Analysis
Botulinum toxin Type A helps reduce hypertrophic scars and is generally safe.
research The Application of Light Emitting Diode (LED ) in Cosmetic Dermatology
LED therapy is a promising, non-invasive skin treatment, but needs standardization and personalization.
research Modern strategies for the prevention and treatment of post-burn scars (a systematic review)
Combining surgical and nonsurgical methods is key to reducing post-burn scars.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
Nanotechnology can improve tissue healing by controlling immune responses.
research Botulinum Toxin in the Treatment of Hair and Scalp Disorders: Current Evidence and Clinical Applications
Botulinum toxin shows promise for treating scalp sweating but not for hair growth.
research Hair Regeneration Methods Using Cells Derived from Human Hair Follicles and Challenges to Overcome
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
research Efficacy of neutral electrolyzed water vs. common topical antiseptics in the healing of full‑thickness burn: Preclinical trial in a mouse model
Superoxidized electrolyzed solution (SES) is more effective for burn healing than common antiseptics.
research Aesthetic Rehabilitation Medicine: Enhancing Wellbeing beyond Functional Recovery
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration
Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
research The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin
Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
research Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations]
Understanding molecular mediators can improve skin healing treatments.
research Stem Cell Therapy for Burns: Story so Far
Stem cell therapy shows promise for better burn healing but needs more research and standardization.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Expression of Snail1 in the fibrotic dermis of postmenopausal frontal fibrosing alopecia: possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients
Snail1 may contribute to fibrosis in frontal fibrosing alopecia in postmenopausal women.
research Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue
Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
research Anagen Hair Follicles Transplanted into Mature Human Scars Remodel Fibrotic Tissue
Transplanted hair follicles can improve and remodel mature scars.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrosis and cancer.
research Mimicking fat grafting of fibrotic scars using 3D‐organotypic skin cultures
Fat grafting reduces scar fibrosis but may slow skin healing.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.
research Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration
Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
research Trichoscopy
Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
research Melanocortins in fibroblast biology – current update and future perspective for dermatology
α-MSH may help treat skin inflammation and fibrosis.