211 citations
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November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
177 citations
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April 2008 in “Biomedical Materials” Human hair proteins can be used to create scaffolds that support cell growth for tissue engineering.
174 citations
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July 2003 in “The Journal of Clinical Endocrinology & Metabolism” Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.
162 citations
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July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
149 citations
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March 1981 in “American Journal of Ophthalmology” Eyelid mites may contribute to eye problems.
140 citations
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April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
138 citations
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December 1976 in “Journal of Biological Chemistry” The enzyme from human skin can cross-link proteins and needs calcium to work.
131 citations
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September 2010 in “The Laryngoscope” Forehead modification greatly increases the perception of femininity and is a safe procedure.
118 citations
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June 1993 in “Journal of Biological Chemistry” Human and mouse TGase3 enzymes are similar but differ near the activation site, crucial for their function in skin and hair development.
89 citations
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March 1990 in “PubMed” Shaving is the most effective temporary hair removal method for facial hirsutism.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
76 citations
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February 1993 in “Journal of Biological Chemistry” KAP6 genes are conserved across species and active in hair follicles.
72 citations
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
69 citations
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
69 citations
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May 1997 in “Veterinary Pathology” The angora mouse mutation causes long hair and hair defects due to a gene deletion.
64 citations
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January 2000 in “The Analyst” Estrone and 17β-estradiol levels in hair differ between males and females.
63 citations
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December 2002 in “Archives of Dermatology” The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
62 citations
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April 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that there's a need for a new conference to establish stricter guidelines for diagnosing Polycystic Ovary Syndrome (PCOS).
61 citations
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November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
60 citations
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May 2018 in “Indian Journal of Psychological Medicine” Women with PCOS often experience anxiety, depression, and a lower quality of life.
58 citations
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December 2000 in “Experimental Dermatology” Involucrin is a useful marker for keratinocyte differentiation in mice.
55 citations
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April 2008 in “Clinical Genetics” A new mutation in the ST14 gene was found in a patient with ARIH syndrome, showing milder symptoms and no tooth issues.
53 citations
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June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
47 citations
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April 2012 in “The Plant Journal” Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.
47 citations
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June 1994 in “Experimental Cell Research” mHa2 and mHa3 keratins have different structures and roles in mouse hair and tongue tissues.
46 citations
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November 1998 in “Experimental Cell Research” K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
45 citations
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September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
42 citations
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August 2016 in “Nanomedicine” The new adapalene formulation using TyroSpheres is more effective and less irritating for acne treatment.
42 citations
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July 2014 in “European journal of pharmaceutics and biopharmaceutics” Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
42 citations
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May 1997 in “The Journal of Biochemistry” PAD type III enzyme is specific to rat skin and hair follicles.