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research Repeated finasteride administration induces depression-like behavior in adult male rats
Finasteride use can cause depression-like behavior in male rats.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Flutamide
Flutamide helps with prostate cancer and some skin conditions but can harm the liver.
research A rapid, simple, liquid chromatographic-electrospray ionization, ion trap mass spectrometry method for the determination of finasteride in human plasma and its application to pharmacokinetic study.
A new method accurately measures finasteride levels in human plasma.
research Cognitive dysfunction following finasteride use: a disproportionality analysis of the global pharmacovigilance database
Finasteride use is linked to increased reports of cognitive problems, especially in younger people with hair loss.
research A Dissolution Test for Finasteride in Immediate-Release Capsules
A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Bioequivalent assessment of finasteride tablets
Locally made finasteride tablets work the same as imported ones.
research TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice
Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.
research Finasteride Induced Cerebral Venous Thrombosis
A man had a rare stroke possibly due to taking finasteride, which might have increased his hormone levels causing a blood clot. His memory loss didn't fully recover even after stopping the medication.
research Pharmacokinetics and Bioequivalence of Finasteride Tablets in Healthy Subjects
The two finasteride tablet formulations are bioequivalent.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Finasteride
Finasteride can cause itching, burning, and other side effects that may not go away after treatment.
research A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism
Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.
research Young patients using finasteride exhibit risk of suicidality
Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.
research Determination of finasteride in the tablet form by liquid chromatography and its analytical method validation
Validated method reliably measures finasteride in tablets using liquid chromatography.
research Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females
Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
research 5α‐reductase inhibitors: Evaluation of their potential confounding effect on GC‐C‐IRMS doping analysis
5α-reductase inhibitors can interfere with doping tests by masking banned substances.
research Flutamide in the treatment of hirsutism
Flutamide effectively reduces hair growth in women with hirsutism and improves acne and seborrhea without side effects.
research Development and evaluation of crystalline inclusion complex of finasteride using electrospraying as a novel approach
Created finasteride complex to increase water solubility and drug release.
research First reboxetine trial results reported
Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
research 5α-Reductase Inhibitors, Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research 471 Senolytic Potential of Fisetin and ABT Compounds in Dermal Fibroblasts
research Determination of finasteride in human plasma by liquid–liquid extraction and high-performance liquid chromatography
Valid method measures finasteride in plasma, simple, fast, and affordable.
research Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study
Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.
research Leflunomide
Leflunomide is effective for rheumatoid arthritis but has significant side effects.
research Effect of finasteride on adrenal steroidogenesis in men.
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research Studies on the stability of finasteride sustained-release tablets
Finasteride sustained-release tablets are stable.