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A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Topical minoxidil does not block androgen effects.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

The compounds tested could potentially treat hair loss and alopecia.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Young and adult hamsters both respond similarly to testosterone and finasteride treatments, but young hamsters aren't good for testing the inhibitory activity of a specific enzyme.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

FGF18 is present in beagle dog hair follicles, mainly in the inner root sheath.

White rhinoceroses have a unique skin structure with thick epidermis and no hair or oil glands.

A patient with untreated congenital adrenal hyperplasia had large benign tumors in her adrenal glands removed, improving her symptoms.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Human sweat glands have a type of stem cell that can grow well and turn into different cell types.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

EZH2 is crucial for uterine gland development and female fertility.

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

MTS24 marks a new type of skin cell that helps hair growth and repair.

Eyelid mites may contribute to eye problems.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The dog's hair loss healed on its own without treatment.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.