82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
80 citations
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May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
77 citations
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July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
77 citations
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February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
77 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
77 citations
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April 2009 in “British Journal of Dermatology” Aromatase gene variation may increase female hair loss risk.
76 citations
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June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
76 citations
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February 2015 in “Industrial Crops and Products” Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
76 citations
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May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
76 citations
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July 2006 in “Veterinary Dermatology” Imiquimod 5% cream reduced equine sarcoids in most cases.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
75 citations
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January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
75 citations
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November 2009 in “Gynecological Endocrinology” Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.
75 citations
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June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
75 citations
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May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
74 citations
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January 2020 in “IEEE Access” ScalpEye accurately diagnoses scalp issues like dandruff and hair loss.
73 citations
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February 2007 in “The American Journal of Medicine” PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.
72 citations
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
71 citations
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November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
70 citations
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April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
70 citations
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January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
70 citations
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April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
69 citations
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July 2015 in “Pharmacotherapy” Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
69 citations
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
68 citations
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September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
68 citations
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November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.