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The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain

70 citations , December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research Temporal Variations of Skin Pigmentation in C57Bl/6 Mice Affect Optical Bioluminescence Quantitation

60 citations , October 2010 in “Molecular Imaging and Biology”

The study investigated the effect of depilation-induced skin pigmentation on bioluminescent imaging in 25 C57Bl/6 mice, finding that increased melanin significantly attenuated the bioluminescent signal by up to 90%. This attenuation was most pronounced at week 3 of a 5-week period, correlating with peak pigmentation. The research emphasized the need for correction methods, such as reflectance measurements, to account for pigmentation variability and improve signal accuracy in longitudinal studies. The findings highlighted the importance of considering skin pigmentation in experimental design to ensure accurate bioluminescent imaging results.

Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata

research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata

59 citations , October 2012 in “Pharmaceutical Research”

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting

57 citations , July 2018 in “Scientific Reports”

Using adipose tissue-derived fragments improves early skin graft success.

research The potential of nestin-expressing hair follicle stem cells in regenerative medicine

50 citations , February 2007 in “Expert Opinion on Biological Therapy”

Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.

research Investigation of Follicular and Non-follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles

47 citations , November 2012 in “Pharmaceutical research”

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs

34 citations , August 2016 in “Scientific Reports”

Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.

research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability

28 citations , January 2013 in “Stem cells”

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat

28 citations , October 2004 in “Differentiation”

A gene deletion causes the "hairless" trait in Iffa Credo rats.

Psoriasis Patients Demonstrate HLA-Cw*06:02 Allele Dosage-Dependent T Cell Proliferation When Treated With Hair Follicle-Derived Keratin 17 Protein

research Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein

27 citations , April 2018 in “Scientific Reports”

Psoriasis patients' immune response to a hair protein depends on their specific gene type.

research Cell Cycle Regulation and Regeneration

27 citations , January 2012 in “Current Topics in Microbiology and Immunology”

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

research Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation

27 citations , August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

23 citations , June 2012 in “PLOS ONE”

KLF4 is important for maintaining skin stem cells and helps heal wounds.

research Effect of ethosomal minoxidil on dermal delivery and hair cycle of C57BL/6 mice

23 citations , October 2006 in “Journal of Dermatological Science”

Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.

Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles for Effective Preservation and Delivery of Fermented Herbal Extract for Enlarging Hair Bulb and Enhancing Hair Growth

research <p>Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth</p>

22 citations , October 2019 in “International Journal of Nanomedicine”

The nanoparticles improved hair growth and enlarged hair bulbs.

A Guide to Studying Human Dermal Adipocytes In Situ

research Minoxidil–2-hydroxypropyl-β-cyclodextrin inclusion complexes: characterization and in vivo evaluation of an aqueous solution for hair growth in rats

16 citations , March 2017 in “Journal of inclusion phenomena and macrocyclic chemistry”

Minoxidil mixed with 2-hydroxypropyl-β-cyclodextrin in water can improve hair growth more than minoxidil alone.

Immunoregulatory Mechanisms and Stress Hormones in Psoriasis (Part 1)

research Androgenetic alopecia in policemen: higher prevalence and different risk factors relative to the general population (KCIS no. 23)

12 citations , September 2011 in “Archives of Dermatological Research”

Policemen have more hair loss due to obesity, sunlight exposure, and stress.

Dutasteride, A Novel Dual 5-Alpha Reductase Inhibitor, Reduces Serum DHT to a Greater Extent Versus Finasteride and Achieves Maximal Reduction in a Larger Proportion of Patients

research Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients

12 citations , February 2003 in “European Urology Supplements”

Dutasteride reduces DHT more effectively than finasteride.

research Tactile sensitivity in the rat: a correlation between receptor structure and function

6 citations , September 2021 in “Experimental Brain Research”

Rats have different touch receptors in their paws that help with movement and handling objects.

Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata

research Increased retinol‐binding protein (RBP) 4 and anti‐RBP4 antibody in alopecia areata

6 citations , June 2011 in “British Journal of Dermatology”

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

research Therapeutic potential of Sertoli cells in vivo: alleviation of acute inflammation and improvement of sperm quality

5 citations , September 2024 in “Stem Cell Research & Therapy”

Sertoli cell transplants can reduce inflammation and improve sperm quality.

research Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture

5 citations , September 2015 in “PLoS ONE”

Gelfoam® histoculture supports long-term hair and nerve growth in mouse whisker follicles.

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