March 2010 in “International Journal of Cosmetic Science” Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
July 1994 in “Annals of Pharmacotherapy” Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
19 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” A special environment is needed to fully activate sleeping stem cells.
137 citations
,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
67 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
32 citations
,
February 2008 in “Developmental dynamics” Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
16 citations
,
September 2016 in “Neuropharmacology” Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Cosmetic procedures can harm hair, but damage can be minimized with knowledge and care; however, once hair is damaged, it cannot be reliably repaired.
January 2009 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” Curved human hair has different structures on each side, which might cause its shape and is similar to wool.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
173 citations
,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
70 citations
,
August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.
70 citations
,
June 1998 in “Polymer” Permanent waving damages hair by disrupting its keratin structure.
65 citations
,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
52 citations
,
April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
47 citations
,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
42 citations
,
January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
40 citations
,
April 1999 in “Journal of Histochemistry & Cytochemistry” S100A3 protein is mainly found in specific parts of human hair cells.
25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
21 citations
,
January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
19 citations
,
January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
15 citations
,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
13 citations
,
March 2022 in “Cell Death and Differentiation” Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
11 citations
,
March 2020 in “Cellular Signalling” XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
10 citations
,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.
8 citations
,
March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
8 citations
,
June 2001 in “Journal of Biological Chemistry” A truncated protein linked to breast cancer may change cell adhesion.
7 citations
,
January 2025 in “ACS Applied Materials & Interfaces” The hydrogel made from egg white and zinc speeds up wound healing.
7 citations
,
October 2019 in “Frontiers in bioengineering and biotechnology” Fusion proteins can protect hair from heat damage.