4 citations
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July 2024 in “Animals” A new depilation method using cold wax reduces injury and improves hair growth studies in mice.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
297 citations
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January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
240 citations
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April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
166 citations
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July 1999 in “American Journal Of Pathology” The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.
159 citations
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December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
119 citations
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November 1969 in “Journal of Ultrastructure Research” Macrophages help break down collagen around hair follicles during hair growth.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
105 citations
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December 1998 in “Archives of Dermatological Research” Dermal papilla cells mainly drive blood vessel growth in hair follicles.
92 citations
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February 2005 in “Endocrinology” Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.
90 citations
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October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
73 citations
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May 2009 in “Proceedings of the National Academy of Sciences” Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.
69 citations
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August 2016 in “PubMed” High stress can disrupt hair growth, but certain supplements might help.
68 citations
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April 1965 in “General and Comparative Endocrinology” The pituitary gland controls seasonal fur color changes in weasels.
66 citations
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October 1999 in “Annals of the New York Academy of Sciences” The Skin POMC System affects hair growth and skin responses to stress.
61 citations
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March 2003 in “American Journal Of Pathology” Stress can cause hair loss and skin issues by affecting hair growth cycles.
53 citations
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May 1990 in “Journal of Dermatology” Minoxidil speeds up hair growth in rats without prolonging growth phase.
43 citations
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December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
42 citations
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July 2017 in “Molecular therapy” A form of vitamin E promotes hair growth by activating a specific skin pathway.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
31 citations
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November 1965 in “Journal of Mammalogy” The pituitary gland is crucial for normal mink fur cycles.
28 citations
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August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
25 citations
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December 2018 in “Journal of Investigative Dermatology” TRPV4 slows hair growth by affecting hair follicle cells.
25 citations
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March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.