January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
Natural products may help treat hair loss by promoting hair growth with fewer side effects.
December 2020 in “Journal of Aesthetic Nursing” Injecting platelet-rich plasma into the scalp stimulates hair growth, increases hair density, and treats hair loss effectively with minimal side effects.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
33 citations
,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
11 citations
,
February 2002 in “International Journal of Cosmetic Science” Recent findings show that hair growth and color are controlled by a complex network of signals in the hair follicle.
2 citations
,
January 2023 in “Frontiers in Genetics” Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
521 citations
,
January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
131 citations
,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
86 citations
,
August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
80 citations
,
January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
14 citations
,
November 2007 in “Journal of Dermatological Science” Vitamin C derivative may promote hair growth by activating specific genes.
7 citations
,
July 2022 in “Pharmaceutics” The microneedle device with rapamycin and epigallocatechin gallate effectively promoted hair regrowth in mice.
6 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.
5 citations
,
January 2017 in “Dermatologic Surgery” Storing hair follicle micrografts for longer times can cause them to enter a state similar to the natural hair shedding phase, which might impact hair transplant results.
2 citations
,
September 2017 in “Mehmet Akif Ersoy Üniversitesi Veteriner Fakültesi dergisi” Specific genes influence hair growth and quality in goats and sheep.
1 citations
,
August 1994 in “Journal of Cutaneous Pathology” Hair loss happens due to faster cell growth and fewer cells in affected follicles.
ISX9 helps regrow hair by activating a specific cell signaling pathway.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” miR-486 may help prevent hair loss in alopecia areata.
September 2017 in “Journal of Investigative Dermatology” Ovol2 is essential for normal skin and hair regeneration.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
March 2013 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Hormones significantly affect hair growth and loss, with potential for new treatments.
October 2012 in “Humana Press eBooks” Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
January 2007 in “Elsevier eBooks” Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
January 2023 in “Iranian Journal of Pharmaceutical Research” Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
5 citations
,
October 2013 in “Experimental Dermatology” The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
February 2025 in “Chemico-Biological Interactions” 5-Fluorouracil causes hair loss by blocking signals needed for hair growth.