research Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing
Mutations in the ST14 gene cause skin and hair issues by disrupting important protein processing.
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research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Evaluation and diagnosis of the hair loss patient
To diagnose hair loss, use a systematic approach including history, exams, and tests.
research Trichotillomania
Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.
research Diffuse hair loss
Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
research Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles
Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
research Hair loss in women: medical and cosmetic approaches to increase scalp hair fullness
Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.
research The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study
Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
research Telogen effluvium
Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
research Alopecia areata: An update
The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
research Approach to the adult female patient with diffuse nonscarring alopecia
The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.
research The cycling hair follicle as an ideal systems biology research model
The hair follicle is a great model for research to improve hair growth treatments.
research Is Androgenetic Alopecia a Photoaggravated Dermatosis?
Sunlight worsens hair loss; protect scalp.
research Dermatosurgical techniques for repigmentation of vitiligo
Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
research Hair follicles as a target structure for nanoparticles
Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research A comparison of vertical versus transverse sections in the evaluation of alopecia biopsy specimens
Using both vertical and transverse sections gives a better diagnosis of alopecia than using one method alone.
research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Chronic telogen effluvium: A study of 5 patients over 7 years
Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.
research Cyclic dynamics of hair follicles and the effect of minoxidil on the bald scalps of stumptailed macaques
Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
research Hair follicles, their disorders and their opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia
Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
research Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid
Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
research Assessment of hair loss: clinical relevance of hair growth evaluation methods
Effective hair loss assessment requires a mix of precise measurement methods.
research Hair through the female life cycle
Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
research Chronic telogen effluvium is due to a reduction in the variance of anagen duration
Chronic hair shedding may be caused by less variation in hair growth times and might stop on its own after several years.
research Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia
Stem cell therapy may help treat tough hair loss cases.
research Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes
Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
research Reflectance Confocal Microscopy of the Yellow Dot Pattern in Alopecia Areata
Reflectance confocal microscopy confirms that yellow dots are signs of damaged hair follicles in alopecia areata.
research Clinical, histopathological and immunological characteristics of exfoliative cutaneous lupus erythematosus in 25 German short‐haired pointers
A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.