479 citations
,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
417 citations
,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
131 citations
,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
36 citations
,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
79 citations
,
November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
556 citations
,
September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
60 citations
,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
53 citations
,
April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
9 citations
,
January 1995 in “Aesthetic Plastic Surgery” New suturing technique with wider intervals and shallow stitches helps prevent scalp scars and promotes hair growth.
8 citations
,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
8 citations
,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
1 citations
,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
February 2026 in “Biochemical and Biophysical Research Communications” Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
39 citations
,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
1 citations
,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
1160 citations
,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
65 citations
,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
28 citations
,
October 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.