Stem cells play a key role in nonmelanoma skin cancers, with different origins and genetic changes linked to basal and squamous cell carcinomas.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
57 citations
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May 2007 in “Nature” Adult mice can grow new hair from skin wounds.
31 citations
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January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
7 citations
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March 2005 in “Journal of dermatological science” Apoptosis helps shape hair growth and prepares the skin for hair to emerge.
2 citations
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December 2011 in “[Thesis]. Manchester, UK: The University of Manchester; 2011.” Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
33 citations
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September 1998 in “Dermatologic Surgery” Surgeons suggested a standard system for hair transplant methods to improve communication and results.
15 citations
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June 2006 in “Journal of Plastic Reconstructive and Aesthetic Surgery” FUT effectively treats male-pattern hair loss with high satisfaction.
August 2013 in “Fertility and Sterility” PCOS may be influenced by factors in the blood, not just the ovaries.
1 citations
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October 2018 in “European Journal of Plastic Surgery” The study found that hair transplant complications are rare, with swelling being the most common issue.
29 citations
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July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
2 citations
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September 2002 in “Dermatologic Surgery” Each group of hair follicles on the scalp shares one muscle that helps control hair movement.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
29 citations
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January 2010 in “PubMed” FUE hair transplants offer minimal scarring and are good for short hairstyles but are time-consuming and can be costly.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
13 citations
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May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
11 citations
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August 2017 in “American Journal of Dermatopathology” EVG staining helps tell apart follicular scars from follicular streamers, aiding in diagnosing different types of hair loss.
10 citations
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January 2013 in “Journal of Cutaneous and Aesthetic Surgery” Narrower donor strips and special closure techniques in hair transplants lead to smaller scars and happier patients.
4 citations
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November 2006 in “Dermatologic Surgery” Transplanted transected hair follicles can survive but grow at unsatisfactory rates and are thinner, suggesting limited potential for unlimited donor hair supply.
1 citations
,
July 2010 in “Dermatologic Surgery” Splitting one hair follicle into two can help regrow hair with a 50% to 70% success rate, useful when donor hair is limited.
New methods efficiently isolate dermal papilla cells from hair follicles, preserving their characteristics better than traditional methods.
November 2006 in “Dermatologic Surgery” Cutting hair follicles into pieces for transplantation results in poor growth and thinner hair, and the technique is more invasive than previously thought.
211 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
13 citations
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March 2012 in “The Journal of Dermatology” Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
316 citations
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
263 citations
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February 2011 in “Journal of Controlled Release” Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
109 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Targeting hair follicles can improve skin treatments and reduce side effects.
69 citations
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December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.