34 citations
,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
19 citations
,
January 2008 in “Journal of Pharmacy and Pharmacology” Porcine hair follicles can effectively model human hair follicles for drug absorption.
3 citations
,
April 2015 in “International research journal of pharmacy” Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
14 citations
,
March 2019 in “European journal of pharmaceutics and biopharmaceutics” Proretinal nanoparticles improve skin absorption and reduce irritation of topical retinoids.
4 citations
,
July 2023 in “Journal of Cosmetic Dermatology” Adapalene microemulsions improve drug delivery through hair follicles, enhancing acne treatment.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
November 2023 in “International Journal of Pharmaceutics” The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
43 citations
,
November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
18 citations
,
January 1997 in “British Journal of Dermatology” 5% topical minoxidil can cause severe body hair growth, which disappears after stopping treatment.
52 citations
,
January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
A new topical treatment using micelles shows promise for safer and more effective hair regrowth in androgenetic alopecia.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
32 citations
,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
2 citations
,
September 2016 in “Journal of Dermatological Science” Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
July 2025 in “International Journal of Biological Macromolecules” A new microneedle system effectively delivers finasteride to treat hair loss.
June 2025 in “Pharmaceutics” Ethosomes with 30% ethanol effectively deliver dutasteride to hair follicles for treating hair loss.
11 citations
,
December 2011 in “International journal of pharmaceutics” Ultrasound increases skin permeability but blocks hair follicles.
8 citations
,
November 2007 in “Skin Pharmacology and Physiology” Stretching skin improves retinyl ascorbate delivery.
May 2025 in “Drug Delivery and Translational Research”
1 citations
,
November 2024 in “Pharmaceutical Sciences” Deformable vesicular carriers improve drug delivery for skin conditions and systemic treatments.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
5 citations
,
March 2016 in “Drug Development and Industrial Pharmacy” New drug delivery systems improve treatment effectiveness and patient experience.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
19 citations
,
July 2020 in “Journal of drug delivery science and technology” Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
25 citations
,
June 2015 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
25 citations
,
July 2015 in “Colloids and Surfaces B: Biointerfaces” Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.