277 citations
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February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
245 citations
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October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
237 citations
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September 2018 in “Clinical Biochemistry” Hair cortisol analysis can help diagnose stress-related conditions but needs more refinement for widespread use.
139 citations
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October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
78 citations
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January 2013 in “Dermatology Online Journal” Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.
26 citations
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September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
9 citations
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September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
4 citations
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July 2022 in “Clinical Cosmetic and Investigational Dermatology” Clascoterone 1% cream is a promising new treatment for acne.
2 citations
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March 2019 in “PubMed” Fusidic acid successfully treated a rare scalp infection with hair regrowth and no recurrence after 6 months.
July 2025 in “Arab Board Medical Journal” NF-κB levels can help diagnose and assess the severity of androgenetic alopecia.
134 citations
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July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
73 citations
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April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
57 citations
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January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
45 citations
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May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
41 citations
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June 2024 in “Journal of Cellular and Molecular Medicine” Natural antioxidants may help prevent hair loss by reducing oxidative stress.
30 citations
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January 2014 in “Journal of Controlled Release” This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
26 citations
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May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
25 citations
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March 2017 in “International Journal of Dermatology” Ruxolitinib effectively and safely regrows hair in alopecia patients.
21 citations
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December 2014 in “Clinics in dermatology” Squaric acid dibutylester effectively treats alopecia areata.
20 citations
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September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” MMP-9 is essential for proper hair canal formation.
18 citations
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October 2024 in “Medical Science Monitor” Improving skin barrier function is crucial for better acne treatment.
18 citations
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February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
16 citations
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March 2017 in “Oncotarget” SOCS3 treatment can prevent hair loss by stopping harmful immune responses.
15 citations
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December 2021 in “Pharmaceutics” The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.
13 citations
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September 2019 in “Clinical, Cosmetic and Investigational Dermatology” Early treatment of EPDS can improve outcomes and reduce recurrence risk.
12 citations
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May 2024 in “Indian Dermatology Online Journal” Probiotics may help treat skin conditions like acne and eczema safely.
11 citations
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October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
10 citations
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February 2022 in “Pharmaceuticals” Smaller curcumin nanocrystals penetrate skin and hair follicles better than larger ones.