256 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
232 citations
,
January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
192 citations
,
March 1998 in “British Journal of Dermatology” Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
178 citations
,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
145 citations
,
November 2017 in “Journal of The European Academy of Dermatology and Venereology” Use minoxidil for hair loss treatment; assess results after 6 months.
102 citations
,
February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
83 citations
,
March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
83 citations
,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
77 citations
,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
68 citations
,
March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
65 citations
,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
61 citations
,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
57 citations
,
February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
55 citations
,
May 2014 in “Journal of feline medicine and surgery” Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.
54 citations
,
October 2019 in “Australian Journal of General Practice” Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.
53 citations
,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
45 citations
,
November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
41 citations
,
January 2011 in “Nippon Ishinkin Gakkai Zasshi” Tinea incognito in Iran commonly affects adults and mimics other skin conditions.
39 citations
,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
39 citations
,
January 2004 in “Physiological Research” Some men with early hair loss may have a condition similar to PCOS in women.
35 citations
,
March 2014 in “British Journal of Dermatology” Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
33 citations
,
September 2007 in “Veterinary dermatology” Topical 0.1% tacrolimus significantly improved ear infections in cats.
31 citations
,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.