49 citations
,
September 2007 in “Journal of Investigative Dermatology” The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
39 citations
,
August 2016 in “Journal of Dermatological Treatment” Stem cell therapy may help treat tough hair loss cases.
37 citations
,
January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
36 citations
,
February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
23 citations
,
November 2017 in “Stem cell investigation” Platelet lysate is more effective than activated autologous platelet-rich plasma or saline in improving hair growth after hair restoration surgery.
15 citations
,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
14 citations
,
January 2013 in “Journal of Cutaneous Medicine and Surgery” Some cancer treatments can cause permanent hair loss.
12 citations
,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
11 citations
,
July 2017 in “Regenerative Medicine” The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
11 citations
,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
10 citations
,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
8 citations
,
March 2020 in “Dermatologic Therapy” The new hair loss treatment kit was safe and improved hair growth without any adverse effects.
7 citations
,
March 2017 in “Medical Hypotheses” Aquaporins could be new drug targets for treating polycystic ovary syndrome.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” Minoxidil can help thicken hair in some people with male pattern baldness, especially if used early and continuously.
6 citations
,
August 2007 in “Journal of Surgical Research” Mice genetically modified to produce more Del1 protein had faster hair regrowth.
3 citations
,
April 2015 in “International research journal of pharmacy” Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
1 citations
,
June 2017 in “Veterinary dermatology” A cross-bred lamb with severe skin and movement issues had ichthyosis fetalis but normal vitamin A levels.
New therapies like JAK inhibitors, PRP, and stem cell treatments show promise for better alopecia management.
January 2024 in “International Journal of Health Science” Scalp cooling and low-power light therapy show promise in reducing chemotherapy-induced hair loss but need more research.
November 2023 in “Curēus” Topical tretinoin effectively treated sebaceous filaments, improving skin appearance.
December 2022 in “Research Square (Research Square)” Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
October 2022 in “Research Square (Research Square)” Key genes linked to immune response are highly active in lupus-affected hair follicles.
March 1998 in “Journal of Dermatological Science” Combining RU58841 and minoxidil significantly increases hair growth.
48 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
19 citations
,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
4 citations
,
January 2013 in “Humana Press eBooks” Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
1 citations
,
April 2010 in “Expert Review of Dermatology” The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
1 citations
,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
13 citations
,
October 2002 in “Journal of Investigative Dermatology” The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.