41 citations
,
June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
29 citations
,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
22 citations
,
December 2014 in “Naunyn-Schmiedeberg's Archives of Pharmacology” Baicalin helps hair grow by boosting certain cell activities and speeding up hair cycle in mice.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
15 citations
,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
13 citations
,
January 2018 in “Cellular Physiology and Biochemistry” Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.
11 citations
,
April 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
6 citations
,
September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
4 citations
,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
3 citations
,
April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
2 citations
,
June 2022 in “Scientific reports” Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
1 citations
,
January 2020 in “Aesthetic Surgery Journal” Platelet-rich plasma and stem cell therapies are accepted treatments for hair restoration, with specific protocols recommended for best results, but more standardization is needed in stem cell use.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
1 citations
,
October 2001 in “Journal of Wood Science” Some extracts from woods and fungi can promote hair growth better than a known hair growth substance.
December 2018 in “The Journal of medical research” The Consciousness Energy Healing Treatment significantly increased human dermal papilla cell growth, suggesting it may help with hair growth and skin disorders.
116 citations
,
May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
1039 citations
,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
508 citations
,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
384 citations
,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
84 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
47 citations
,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
42 citations
,
September 2015 in “Gene” FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
33 citations
,
April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
32 citations
,
August 2019 in “Nature Communications” Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.