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A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.
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210-240 / 1000+ resultsresearch Sequential small-molecule therapy for lymphocytic cicatricial alopecia: A multicenter prospective cohort pilot study
The treatment significantly improved lymphocytic cicatricial alopecia symptoms in most patients.
research Follicular Psoriasis: A Case Report and Review of Literature
A man with follicular psoriasis got better after treatment with skin cream and allergy pills.
research Diffuse Alopecia With Stem Cell Folliculitis
Lymphocytes may hinder hair stem cells, causing hair loss without scarring.
research Multiple Scaly Patches on the Scalp
Itraconazole is effective for treating scalp ringworm, and a Wood's lamp is a useful diagnostic tool.
research Wolf's isotopic response: Trichophyton rubrum folliculitis appearing on a herpes zoster scar
A fungal infection developed on a herpes scar and was successfully treated with antifungal medication.
research M-CSF-Stimulated CD11b+ Myeloid Cells Induce Alopecia Areata in C3H/HeJ Mice
M-CSF-stimulated myeloid cells can cause alopecia areata in mice.
research Perifollicular erythematous papules on the scalp
The woman has a type of scarring hair loss with red bumps around hair follicles.
research Necrobiosis lipoidica of the scalp
A rare scalp condition caused scarring hair loss in a woman, improved slightly with treatment.
research Dermoscopic image of the hairs in a very early lesion of tinea capitis caused by Trichophyton rubrum
Early detection of tinea capitis is possible by spotting specific hair patterns like comma or corkscrew hairs.
research Multiple pigmentierte Basaliome im Capillitium bei Myotonia dystrophia Curschmann-Steinert
A woman with myotonic dystrophy had multiple skin tumors on her scalp, suggesting a genetic link.
research Folliculitis decalvans mimicking lupus vulgaris successfully treated with minocycline and clarithromycin
A rare scalp condition was successfully treated with minocycline and clarithromycin.
research Hodgkin′s lymphoma presenting as alopecia
Hodgkin's lymphoma can show up as hair loss.
research The role of lymphocytes in the development and treatment of alopecia areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Majocchi's Granuloma in a High School Wrestler
A high school wrestler's skin rash was cured with antifungal medication after a misdiagnosis and incorrect treatment led to a fungal infection.
research Hypopigmented facial lesions: a case of eruptive tumor of follicular infundibulum
Consider TFI in facial hypopigmentation diagnoses and confirm with a biopsy.
research Kerion
The boy had a fungal scalp infection called kerion, which was cured with oral antifungal medication.
research Nonscalp hair infection caused by Microsporum canis in patient with acquired immunodeficiency syndrome
research Feline dermatophytosis
Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.
research 584 Dandruff is associated with perturbations of hair follicle immune privilege, and the infundibular and epidermal immune microenvironment
Dandruff is linked to changes in the immune system of hair follicles and skin.
research Folliculitis decalvans including tufted folliculitis: clinical, histological and therapeutic findings
Folliculitis decalvans and tufted folliculitis are related, and a new treatment with rifampicin and clindamycin is effective.
research 039 Expansion of regulatory T Cells restrains pathogenic CD8 T Cells in a murine model of alopecia areata
Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.
research Trichofolliculoma of the Scalp: A Rare Case Report
Trichofolliculoma is a rare, benign scalp tumor that can be cured by surgical removal.
research Viral-associated trichodysplasia in patients who are immunocompromised
Immunocompromised patients can develop skin and hair issues due to a virus.
research Lichen Amyloidosis on the Scalp: A Case Report
Topical treatment improved rare scalp lichen amyloidosis.
research An Unusual Case of Tinea Capitis Presented as Erythematous, Hyperkeratotic, Scaly Plaque with Alopecia
Tinea capitis can occur in adults and should be considered if scalp issues persist.
research Generation of autoreactive CD8 T cell in a mouse model of alopecia areata
Alopecia areata involves unique activation of certain immune cells.
research PHILADELPHIA DERMATOLOGICAL SOCIETY
Dermatological conditions are complex and treatments often have mixed results.
research Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss
This study investigates the interactions between T cells and hair follicles in cutaneous lupus erythematosus (CLE) across mice, dogs, and humans, focusing on the role of these interactions in skin disease and hair loss. The research identifies a 35% overlap in gene expression when autoreactive T cells are transferred in mice, with CD8 T cells contributing to extracellular matrix reorganization. Key findings include the identification of CXCR3 ligands and IFN response genes in hair follicles, conserved across species, and the alleviation of skin disease in mice through CXCR3 knockout on T cells. B cell depletion also reduces skin disease, aligning with human lupus therapies. The study highlights CFD and S100A8/9 as potential targets for future trials, emphasizing the role of CXCR3+ T cells and B cells in CLE lesional skin and their contribution to hair loss and inflammation.
research Methotrexate-associated lymphoproliferative disorder: Sequential development of angioimmunoblastic T-cell lymphoma-like lymphoproliferation in the lymph nodes and diffuse large B-cell lymphoma in the skin in the same patient
Stopping methotrexate might reverse lymphoma-like conditions in some patients.