research A syndromic extreme insulin resistance caused by biallelic POC1A mutations in exon 10
Mutations in the POC1A gene can cause a unique form of extreme insulin resistance and short stature.
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870-900 / 1000+ results research Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX 2 and SOX 9 in the human hair follicle
LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
research LB1604 The role of polyunsaturated fatty acids on hair growth
Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.
research Foxn1 promotes keratinocyte differentiation by regulating the activity of protein kinase C
Foxn1 helps skin cells mature by controlling a specific protein's activity.
research Generation of a Novel Inducible and Dermal Papilla‐Specific Wif1‐CreER Knock‐In Mouse Line for Hair Follicle Research
A new genetic tool improves the study of hair growth and potential hair disorder treatments.
research Direct reprogramming of human fibroblasts into hair-inducing dermal papilla cell-like cells by a single small molecule
Peficitinib can turn human fibroblasts into cells that help grow hair.
research Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Vitamin D3Analogs Stimulate Hair Growth in Nude Mice
Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research 602 Sox13 is a novel marker for hair follicle development and differentiation
Sox13 is a new marker for early hair follicle development and differentiation.
research In vivo alteration of the keratin 17 gene in hair follicles by oligonucleotide‐directed gene targeting
Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.
research Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research G4, is a new transgenic mouse model for the polycystic ovaries syndrome
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
research Pseudofolliculitis barbae; current treatment options
The document concludes that stopping shaving or removing affected hair can alleviate Pseudofolliculitis barbae (PFB).
research Reproducibility package for an auditable exploratory re-analysis of miRNA dysregulation and aging-related validated target enrichment in female pattern hair loss
The study provides exploratory findings on miRNA changes in female hair loss.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different fish use the same genes to regrow teeth.
research 584 Transcriptomic analysis to identify protective dermal papilla signature in occipital scalp
The research found genes that may protect certain scalp cells from hair loss.
research NovelPAX9mutation associated with syndromic tooth agenesis
A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.
research Structural variation-driven FADS2P1 expression modulates hair trait diversity through unsaturated fatty acid metabolism in goats
research Hox demarcates regional regeneration of adult hair follicle stem cells
Hox genes control hair follicle stem cell regeneration in different body regions.
research The KRAB domain zinc finger protein, Zfp157 , is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin
Zfp157 is active in many mouse tissues during development and in specific adult cells.
research MEGA PROTAC, MEGA DOCK-based PROTAC mediated ternary complex formation pipeline with sequential filtering and rank aggregation
MEGA PROTAC improves prediction and ranking of protein complexes better than existing methods.
research Hirsutism
The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.
research Why Some Women Look Young for Their Age
Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles
The new "differential stripping" method effectively measures how much substance gets into hair follicles.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research Androgenetic Alopecia
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research Physiological changes in the skin during pregnancy
Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
research Topical minoxidil in the treatment of alopecia areata.
Minoxidil helps hair regrowth in alopecia patients, with 16 having good results and no side effects.