research Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies
Eflornithine improved symptoms in Bachmann–Bupp Syndrome patients.
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research Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery
LCN may improve finasteride delivery for hair loss treatment.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study
CG2001 is safe and well-tolerated for treating hair loss in men.
research Mycorrhiza-induced changes in root growth and nutrient absorption of tea plants
AMF inoculation boosts tea plant growth and nutrient absorption.
research بررسی اثر ژل دانه گیاه شنبلیله (. Trigonella foenum-graecum L) در پیشگیری از موخوره در یک کارآزمایی بالینی تصادفی کنترل شده با پلاسبوEvaluation of Gel Formulation of Trigonella foenum-graceum Seed on prevention of Trichoptilosis in randomized placebo controlled Clinical Trial
Fenugreek gel significantly reduces split ends and improves hair health.
research Male Pattern Alopecia Regrowth Following Topical Fluorouracil Therapy
A man regrew hair after using a 2% fluorouracil treatment on his scalp.
research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity
XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
research Optimization of finasteride nano-emulsion preparation by using chemometrics approaches (and/or Box-Behnken design and regresion model)
research Modulation of AR-FGF-2-TGF beta Axis by Cosmos caudatus Suppresses Prostatic Epithelial Proliferation in a BPH Rat Model: A Comparative Study with Finasteride
Cosmos caudatus extract is as effective as finasteride for treating benign prostatic hyperplasia without its side effects.
research Faculty Opinions recommendation of Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis.
research Post-menopausal frontal fibrosing alopecia
The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.
research The Post-Finasteride Syndrome After Distinct Doses/Affections
research Testosterone stimulates proliferation and inhibits interleukin‐6 production of normal and hereditary gingival fibromatosis fibroblasts
Testosterone increases cell growth and reduces IL-6 in gum cells.
research Oral Administration of TrkB Agonist, 7, 8–Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin–Induced Vestibular Injury in Guinea Pig
research Therapeutic response of facial papules and inflammation in frontal fibrosing alopecia to low-dose oral isotretinoin
Low-dose oral isotretinoin improved hair loss and facial bumps in patients with a specific type of hair loss.
research Efeitos da finasterida sobre culturas de células epiteliais prostáticas normais e tumorais em diferentes sistemas in vitro
Finasteride may reduce prostate tumor cell invasion and spread.
research Sinapic Acid Promotes Browning of 3T3‐L1 Adipocytes via p38 MAPK/CREB Pathway
Sinapic acid may help fight obesity and promote hair growth.
research Alopecia fibrosante frontal
Frontal fibrosing alopecia causes hairline recession and eyebrow loss in postmenopausal women.
research 112 Post-Finasteride Syndrome – Outcomes of FDA Database
research Protein profiling of forehead epidermal corneocytes distinguishes frontal fibrosing from androgenetic alopecia
Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.
research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research Efficacy and tolerability of finasteride 1 mg in men aged 41 to 60 years with male pattern hair loss.
Finasteride 1 mg significantly improves hair growth in men aged 41 to 60 with male pattern hair loss.
research Robust Metformin Nanosystem Promotes Hair Growth in Androgenetic Alopecia
A new metformin-based treatment may effectively promote hair growth with fewer side effects.
research Combination therapy with topical minoxidil and nano-microneedle-assisted fibroblast growth factor for male androgenetic alopecia: a randomized controlled trial in Chinese patients
Combining minoxidil and fibroblast growth factor is more effective for treating male hair loss than using either alone.
research Efeitos de diferentes doses do Minoxidil oral, em dois tempos de exposição, no complexo prostático de camundongos Balb/C
Oral minoxidil affects prostate tissue but is less harmful than finasteride.
research 5% Minoxidil: treatment for female pattern hair loss.
5% minoxidil foam effectively treats female hair loss.
research Significance of RU58841 as a therapeutic agent effecting androgen receptor molecular interactions in human hair follicles.
RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.