488 citations
,
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318 citations
,
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277 citations
,
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245 citations
,
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227 citations
,
April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
214 citations
,
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200 citations
,
March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
181 citations
,
January 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
181 citations
,
December 2017 in “Trends in immunology” Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
177 citations
,
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