5 citations
,
December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.
19 citations
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December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
April 2021 in “Journal of Investigative Dermatology” Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.
7 citations
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March 2007 in “International Journal of Dermatology” Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
28 citations
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November 2013 in “Cell and Tissue Research” 5 citations
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July 2004 in “Journal of Investigative Dermatology” Understanding Wnt-β-catenin signaling is key to hair growth and could impact conditions like baldness.
December 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology”
14 citations
,
January 2017 in “Pharmacological Reports” TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
114 citations
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May 2001 in “Development” Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.
60 citations
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July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
July 2022 in “Journal of Investigative Dermatology” Dkk4 is necessary for the initial development and arrangement of hair follicles.
October 2023 in “International journal of molecular sciences” Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
4 citations
,
May 2025 in “npj Parkinson s Disease” PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
1 citations
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January 2025 in “American Journal of Translational Research” PPARα agonists may help treat alopecia areata by reducing inflammation.
10 citations
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December 2018 in “Medical Science Monitor” The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.
2 citations
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June 2017 in “Journal of biomedicine and translational research” Lychee fruit polyphenol (Oligonol®) may regulate genes linked to cell growth and inflammation in human scalp cells.
Raptor and Rictor have stable expression in hair cycles, with Raptor marking stem cells and Rictor involved in hair shaft formation.
May 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.
43 citations
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January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
14 citations
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October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
2 citations
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November 2017 in “Gynecological Endocrinology” The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.
8 citations
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October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
11 citations
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July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
1 citations
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June 2000 in “PubMed” Osteopontin may help hair follicle growth during the catagen phase.
11 citations
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October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
January 2026 in “Biomedicines” Dysregulated lipid metabolism may play a role in male pattern baldness.
1 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.