25 citations
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November 2017 in “Molecular Medicine Reports” PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
February 2026 in “Applied Biosciences” The study found potential new DNA patterns in fertility genes, but further testing is needed.
3 citations
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June 2021 in “Frontiers in genetics” The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
28 citations
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February 2007 in “Cancer Research” Blocking certain proteins in mouse skin can reduce and shrink skin tumors.
1 citations
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December 2018 in “IOP conference series. Materials science and engineering” CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.
65 citations
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March 2004 in “Journal of Clinical Investigation” Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
54 citations
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October 2007 in “The FASEB Journal” Phospholipase C-δ1 is crucial for normal hair development.
7 citations
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February 2025 in “Stem Cell Research & Therapy” Human hair follicle stem cells improve ovarian function in mice with damaged ovaries.
15 citations
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November 2023 in “Immunity & ageing” TLR4 is important in aging-related diseases and could be a new treatment target.
33 citations
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March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
November 2025 in “Journal of Investigative Dermatology” Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
November 2023 in “Animal Bioscience” miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
83 citations
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February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
July 2025 in “Journal of Investigative Dermatology” Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.
7 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
December 2023 in “Journal of Investigative Dermatology” A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.
11 citations
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March 2020 in “Cellular Signalling” XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
March 2026 in “Preprints.org” Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
1 citations
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May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
19 citations
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December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
8 citations
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October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
September 2016 in “Journal of Dermatological Science” Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
January 2026 in “Scientific Reports” PCOS involves immune and genetic factors, with key roles for T cells and specific genes.
218 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
69 citations
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
1 citations
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August 2016 in “Journal of Investigative Dermatology” Vδ1+ T-cells in the skin contribute to hair loss in alopecia areata and could be targeted for treatment.
165 citations
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September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
85 citations
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May 2009 in “Hippocampus” Progesterone helps adult male mice grow more neurons and improves memory.