123 citations
,
August 2005 in “Journal of the European Academy of Dermatology and Venereology” The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.
1 citations
,
October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
28 citations
,
January 2008 in “Journal of medical investigation” Sp6 promotes tooth development by reducing follistatin levels.
January 2016 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” A 6-group geometric classification of human scalp hair is more reliable and objective for testing than an 8-group system.
30 citations
,
October 1999 in “Differentiation” Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.
7 citations
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July 2004 in “International Journal of Cosmetic Science” Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.
1 citations
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April 2017 in “Journal of Investigative Dermatology” D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.
97 citations
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March 2010 in “The American Journal of Human Genetics” A mutation in the KRT74 gene causes tightly curled hair.
February 2024 in “Skin research and technology” The research suggests that immune cells and a specific type of cell death called ferroptosis are involved in Frontal fibrosis alopecia.
32 citations
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February 2008 in “Developmental dynamics” Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
7 citations
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January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry” February 2023 in “Cosmoderma” January 2016 in “Indian dermatology online journal” Frontal fibrosing alopecia causes hair loss at the front hairline, and no effective treatment exists.
1 citations
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June 2025 in “Journal of Clinical Medicine” Frontal fibrosing alopecia often occurs after menopause, with delayed diagnosis and possible links to certain medications and conditions.
November 2021 in “CRC Press eBooks” Hair shaft disorders cause fragile, brittle, and abnormal-looking hair.
34 citations
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June 2020 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
49 citations
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April 2007 in “Pediatric Dermatology” Biotin improved hair appearance in uncombable hair syndrome but didn't change hair structure.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” February 2024 in “Medicina” AFM can diagnose hair disorders by revealing detailed hair surface changes.
55 citations
,
August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
September 2024 in “Journal of the American Academy of Dermatology” Phenoxyethanol in hair growth products may be linked to frontal fibrosing alopecia.
July 2015 in “Journal of the Dermatology Nurses’ Association” A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.
January 2024 in “Asian Journal of Medical Sciences” Dermoscopes help tell FPHL apart from other hair loss types and can detect it early by identifying specific patterns.
Early diagnosis and treatment of frontal fibrosing alopecia are crucial to prevent permanent hair loss.
5 citations
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March 2009 in “Pediatric Dermatology” The study found that pili bifurcati causes hair to intermittently split into two branches, each with its own outer layer.
September 2025 in “Brazilian Journal of Health Review” Early diagnosis and less aggressive hair care improve outcomes for Black women with frontal fibrosing alopecia.
September 2025 in “Digital Commons - RU (Rockefeller University)” FOXC1 is essential for keeping hair follicle stem cells inactive and maintaining their environment for healthy hair growth.
53 citations
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June 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Frontal fibrosing alopecia mainly affects postmenopausal women and may be linked to thyroid hormones.