October 2022 in “Frontiers in Genetics” The research found new potential mechanisms in mouse hair growth by studying RNA interactions.
April 2023 in “IntechOpen eBooks” Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
55 citations
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November 2010 in “Development” Hair follicles in mutant mice self-organize into ordered patterns within a week.
4 citations
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April 2015 in “Experimental Dermatology” Certain genes controlled by OVOL1 are crucial for creating new hair follicles.
A protein called sFRP4 can partly inhibit hair growth.
sFRP4 partially inhibits hair regeneration, but the study needs clearer data analysis and better explanation of the process.
99 citations
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July 2012 in “PLoS Genetics” A mutation in the KRT75 gene causes frizzle feathers in chickens.
2 citations
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June 2024 in “Journal of the Pakistan Medical Association” Higher SFRP-4 levels were found in people without a diabetic family history.
92 citations
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April 2009 in “Journal of Investigative Dermatology” The Celsr1 gene is crucial for normal hair patterning in mice.
91 citations
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December 2006 in “Proceedings of the National Academy of Sciences” Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
29 citations
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February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
28 citations
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October 2014 in “Development” Fz3 and Fz6 can partially replace each other in tissue polarity and axon guidance.
7 citations
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January 2011 Collagen XVIII is crucial for maintaining tissue structure and function in the brain, kidneys, and hair.
May 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
June 2021 in “National Medical Journal of China” Bimatoprost helps mouse hair grow by turning on a specific growth pathway.
May 2018 in “Endocrine Abstracts” SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
December 2024 in “Regenerative Therapy” Inhibiting SFRP1 may help treat hair loss.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
January 2016 in “Experimental Dermatology” New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
November 2017 in “Koubunshi rombunshuu/Kōbunshi ronbunshū” Hematin in shampoo helps repair and straighten damaged hair.
Frizzy hair is fragile and can lead to hair loss and damage if not properly cared for.
December 2025 in “Nature Communications” Club-like receptors detect light touch but not whisking.
28 citations
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February 2010 in “Experimental Dermatology” The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.
15 citations
,
December 1972 in “Journal of Investigative Dermatology”
66 citations
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April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
January 1992 in “Biology of the Cell” Retinoic acid receptors are important for hair follicle development.
October 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” A new type of nerve cell involved in itch perception was discovered.
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Excessive sun protection might contribute to frontal fibrosing alopecia.
July 2024 in “Journal of Investigative Dermatology” Linalool in fragrances may harm hair follicles and contribute to hair loss.