155 citations
,
September 2008 in “British journal of dermatology/British journal of dermatology, Supplement” FFA is more common in postmenopausal women, can affect younger women, and may stabilize over time.
128 citations
,
March 2006 in “American Journal of Pathology” Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
123 citations
,
August 2005 in “Journal of the European Academy of Dermatology and Venereology” The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.
117 citations
,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
86 citations
,
July 2012 in “British journal of dermatology/British journal of dermatology, Supplement” There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.
64 citations
,
June 2009 in “Journal of The American Academy of Dermatology” Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.
46 citations
,
January 2015 in “Journal of The American Academy of Dermatology” Trichoscopy helps diagnose and assess the severity of Frontal Fibrosing Alopecia.
43 citations
,
August 2013 in “Pediatric Dermatology” Trichoscopy is good for diagnosing and monitoring hair and scalp problems in children but needs more research for certain conditions.
40 citations
,
December 1980 in “The Journal of Dermatologic Surgery and Oncology” An improved scalp reduction technique reduces the need for hair grafts and has minimal complications.
39 citations
,
July 2015 in “British Journal of Dermatology” The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.
38 citations
,
March 2017 in “Expert Opinion on Investigational Drugs” Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.
37 citations
,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
36 citations
,
December 2017 in “Journal of the American Academy of Dermatology” Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.
33 citations
,
January 2015 in “Journal of Cosmetic Dermatology” Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.
32 citations
,
June 2003 in “The American Journal of Dermatopathology” Lipedematous scalp is mainly caused by an increase in fat tissue under the skin and is different from lipedematous alopecia.
29 citations
,
July 2010 in “Journal of Cutaneous Medicine and Surgery” Treatments for Frontal Fibrosing Alopecia have not been proven effective.
28 citations
,
July 2002 in “Dermatologic Surgery” Understanding scalp anatomy is crucial for successful and safe scalp surgery.
26 citations
,
October 2018 in “British Journal of Dermatology” Regular use of sunscreen may be linked to frontal fibrosing alopecia.
25 citations
,
December 2017 in “Facial Plastic Surgery” Combination therapy with steroids and pimecrolimus improved or stabilized hair loss in most patients with Frontal Fibrosing Alopecia, who also had a high rate of hypothyroidism.
23 citations
,
January 2016 in “Transgender health” Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
21 citations
,
October 2011 in “British Journal of Dermatology” Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
21 citations
,
August 1991 in “The Journal of Dermatologic Surgery and Oncology” Using tissue expanders and hyaluronidase in scalp reduction surgery allows for more scalp removal and easier surgery.
19 citations
,
September 2011 in “Clinical and Experimental Dermatology” Transverse scalp sections are better for diagnosing non-scarring hair loss, while vertical sections are better for a specific scarring hair loss called lichen planopilaris.
18 citations
,
June 2017 in “Journal of The American Academy of Dermatology” Trichoscopy helps diagnose frontal fibrosing alopecia, even with unusual patterns.
18 citations
,
November 2012 in “Australasian Journal of Dermatology” A 66-year-old man with a rare case of male frontal fibrosing alopecia did not regrow hair despite treatment.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
16 citations
,
November 2013 in “European Journal of Dermatology” Hair gets thinner and grayer with age, and density decreases more in men on top and in women on top and back.
16 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” The document concludes that there are no reliable treatments for frontal fibrosing alopecia, with only temporary benefits from current options.
16 citations
,
October 1979 in “The Journal of Dermatologic Surgery and Oncology” Scalp reduction surgery successfully reduced baldness and improved self-image in a burn victim before hair transplantation.
14 citations
,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.