59 citations
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January 2021 in “Genes” Twelve key genes may improve cashmere production by influencing hair follicle cycles.
29 citations
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December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
4 citations
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November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
9 citations
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February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
68 citations
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April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
May 2006 in “The Journal of Cell Biology” Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
6 citations
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June 1976 in “Journal of Investigative Dermatology” 26 citations
,
January 1992 in “Carcinogenesis” TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
27 citations
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August 2013 in “Cell Proliferation” Understanding tooth development pathways may help regenerate teeth and treat dental issues.
September 2019 in “Journal of Investigative Dermatology” Sox13 is a new marker for early hair follicle development and differentiation.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
30 citations
,
January 2013 in “Human Mutation” A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.
638 citations
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October 1997 in “Nature” The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
11 citations
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March 2013 in “Journal of Applied Biomedicine” β-catenin helps hair follicle stem cells grow by activating a specific cell pathway.
January 2013 in “eScholarship (California Digital Library)” Activating Wnt signaling improves the efficiency and safety of creating stem cells.
12 citations
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April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
1 citations
,
July 2022 in “British Journal of Dermatology” Targeting specific genes in certain pathways may help treat male pattern baldness.
Understanding wound healing and signaling pathways could lead to new alopecia treatments.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
October 2025 in “Proceedings of the National Academy of Sciences” Phospholipids help plant proteins move by regulating receptor interactions.
5 citations
,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
3 citations
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September 2021 in “Journal of Clinical Medicine” Epidermal signaling helps regenerate fingertip tissue.
19 citations
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April 2015 in “International Journal of Molecular Sciences” The research identified genes and pathways important for sheep wool growth and shedding.
161 citations
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August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
43 citations
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September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.