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The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

New gene variants linked to a rare inherited hair loss disorder were found in three Chinese families.

Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.

The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

Certain gene variations in EGF and EGFR may increase the risk of alopecia areata in Koreans.

NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.

Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

Colorectal cancer's ability to spread is due to changes in many genes, not just one.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

The rs1128977 gene variant may affect cholesterol and body measurements.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

Mutations in the KLHL24 gene cause a skin disorder in some Russian families.

A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.

Injury boosts normal skin cell growth, reducing cancer cell advantage.

Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.

The ZIP13 variant is linked to abnormal hair quality.

HPV type 56 can hide in hair follicles even without visible warts.

A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.

A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

RXRα is crucial for hair growth and skin cell function.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

The angora mouse mutation causes long hair and hair defects due to a gene deletion.

GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.

Mutations in the DSG4 gene cause a severe form of brittle hair and skin issues.