April 2022 in “Medicinus” Effective treatments for common hair loss are limited and may have side effects, leading to patient disappointment and treatment discontinuation.
35 citations
,
March 2011 in “International Journal of Dermatology” No true link between AGA and insulin resistance, but coexistence may worsen AGA.
59 citations
,
July 1972 in “Biochemistry” Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
8 citations
,
May 2024 in “PLoS Biology” Gap junctions help control feather pattern formation in chickens.
28 citations
,
November 2009 in “European Journal of Neuroscience” Progesterone and allopregnanolone increase glycine release in rat brain cells.
2 citations
,
January 2022 in “BioMed Research International” Gujian oral liquid reduces osteoarthritis symptoms by targeting inflammation.
May 2025 in “Medical Science Monitor” Concentrated growth factor shows promise for treating hair loss but needs more research.
3 citations
,
January 2021 in “Journal of The American Academy of Dermatology” Different types of atopic dermatitis were linked to specific genetic and immune changes, suggesting that severe cases might need stronger immune-targeting treatments.
54 citations
,
January 1984 in “Molecular and Cellular Biochemistry”
40 citations
,
June 2009 in “Journal of Cutaneous Pathology” AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
39 citations
,
January 2020 in “Frontiers in Genetics” PDGFC gene may help select goats with desirable curly wool traits.
14 citations
,
December 2016 in “Sexual Medicine” Finasteride side effects in young men may be linked to specific gene variations.
19 citations
,
August 2008 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
11 citations
,
June 2012 in “Acta histochemica” Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
91 citations
,
May 1972 in “Journal of Biological Chemistry” Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.
Arginine deficiency hinders hair growth in androgenetic alopecia, but restoring it can promote hair regeneration.
2 citations
,
July 2011 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” Seven genetic variations in sheep's DSG4 gene are linked and affect wool traits.
22 citations
,
August 2009 in “Evidence-based Complementary and Alternative Medicine” The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.
2 citations
,
February 2024 in “Medicine” A mutation in the IL2RA gene increases the risk of alopecia areata.
1 citations
,
November 2019 in “The Korea Journal of Herbology” The herbal mixture RAA promotes hair growth and could be an alternative treatment for hair loss.
July 2020 in “Benha Journal of Applied Sciences” Young men with early hair loss and high SAA3 levels are at higher risk for heart disease.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
April 2008 in “Blackwell Publishing Ltd eBooks” AGA causes permanent hair loss; minoxidil helps men, finasteride helps men, minoxidil somewhat helps women, estrogens/antiandrogens lack evidence for women.
April 2007 in “Linchuang pifuke zazhi” TGF-β1 and 2 may play a role in hair loss in AGA.
January 2026 in “Journal of Dermatological Treatment” GT20029 showed some hair growth improvement, but longer studies are needed for better results.
December 2023 in “Benha Journal of Applied Sciences” AGEs and their receptors play a significant role in hair loss by causing inflammation and oxidative stress.
September 2024 in “Journal of the American Academy of Dermatology” Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.
January 2015 in “Journal of North Sichuan Medical College” Androgenetic alopecia is more common in males, can be influenced by lifestyle, and may be linked to other skin issues.
11 citations
,
October 2002 in “Genetics” A new mouse hair mutation, called hague, is semidominant and unstable, but the exact cause is unknown.
March 2026 in “International Ayurvedic Medical Journal” Gunja has potential for hair growth, fertility control, immune support, and more, but needs careful handling due to toxicity.