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A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

research A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

17 citations , September 2014 in “PLoS ONE”

SK2 channels help control sensory signals in rat muscle spindles and hair follicles.

research Modulation of neuropeptide Y and Y₁ receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y₁R/LacZ transgenic mice

15 citations , November 2007 in “Journal of Neurochemistry”

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands#

16 citations , November 2018 in “Medicinal Chemistry”

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

research Increased expression of the gene for the Y₁ receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y₁R/LacZ transgenic mice in response to restraint stress

22 citations , April 2004 in “Journal of Neurochemistry”

Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.

research Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-?1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles

32 citations , July 2003 in “Histochemistry and Cell Biology”

research Effects of Potassium Channel Modulators on the Responses of Mammalian Slowly Adapting Mechanoreceptors

January 2022 in “Social Science Research Network”

Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.

research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.

September 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.

research Reviewer #1 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells

January 2024

CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.

research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice

5 citations , January 2015 in “Molecular Genetics and Metabolism”

research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus

November 2019 in “Synapse”

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus

19 citations , September 2006 in “Journal of Neurophysiology”

Neurosteroids help balance brain signals when certain inhibitions are reduced.

research Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

7 citations , March 2022 in “Scientific reports”

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

research The Agouti Gene in Obesity: Central and Peripheral Mechanisms, and Therapeutic Implications

May 2001

The agouti gene may help understand and treat obesity.

Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research Changes in expression of the neuropeptide Y Y₁ receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery

12 citations , September 2002 in “Journal of Neurochemistry”

Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.

Benzothiazepines, Diltiazem, and JTV-519 Exert Anxiolytic-Like Effects via Neurosteroid Biosynthesis in Mice

research Benzothiazepines, diltiazem and JTV-519, exert an anxiolytic-like effect via neurosteroid biosynthesis in mice

1 citations , March 2020 in “Journal of Pharmacological Sciences”

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation

19 citations , September 2013 in “Psychoneuroendocrinology”

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Sigma-1 Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward

research ς_{1sub>Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward}

100 citations , May 2003 in “Journal of Neuroscience”

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

research Glyburide blocks the relaxation response to BRL 34915 (cromakalim), minoxidil sulfate and diazoxide in vascular smooth muscle.

90 citations , January 1989 in “PubMed”

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K_ATPChannel Mutations in Intact Cells

1 citations , August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

research The interaction of CaM7 and CNGC14 regulates root hair growth inArabidopsis

46 citations , November 2019 in “Journal of Integrative Plant Biology”

CaM7 and CNGC14 interaction controls root hair growth in Arabidopsis.

A Novel Effect of Glycine on Root System Growth of Habanero Pepper

research A Novel Effect for Glycine on Root System Growth of Habanero Pepper

14 citations , November 2013 in “Journal of the American Society for Horticultural Science”

Glycine slows main root growth but boosts root hair growth in habanero peppers.

research Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth

34 citations , April 2018 in “EMBO journal”

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development

142 citations , March 2019 in “Frontiers in Cellular Neuroscience”

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.