288 citations
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January 2001 in “Journal of Biological Chemistry” Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
17 citations
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April 2023 in “Aging” CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.
20 citations
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January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
Onabotulinum toxin A may help treat trichotillomania and promote hair growth.
4 citations
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September 2025 in “Biomolecules” The effect of GLP-1 RAs on erectile function is unclear and needs more research.
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.
6 citations
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July 2016 in “Doklady Biochemistry and Biophysics” GD-23 reduces anxiety by relying on neurosteroid production.
2 citations
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April 2012 in “Science-business Exchange” Blocking a protein called prostaglandin D2 might help treat hair loss.
February 2025 in “medRxiv (Cold Spring Harbor Laboratory)” GLP-1 agonists may increase the risk of hair loss.
358 citations
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January 1968 in “Physiological Reviews” Histamine plays key roles in immune responses, stomach acid, and brain signals.
21 citations
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May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry” Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
1 citations
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January 2022 in “Wiadomości Lekarskie” GERD symptoms are linked to acid exposure time and daytime sleepiness, influenced by ghrelin levels.
10 citations
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December 2017 in “Chemosphere” Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
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July 2019 in “Journal of Cosmetic Dermatology” New shampoo with tyramine hydrochloride reduces hair loss by making a small muscle in the hair follicle contract.
24 citations
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July 1994 in “Molecular Endocrinology” Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
CCC1 is essential for pH balance and normal cell function in plants.
CCC1 is essential for ion balance and proper plant cell function.
January 2017 in “SHILAP Revista de lepidopterología” Agomelatine might help reduce hair loss caused by valproate.
RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
23 citations
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June 1992 in “PubMed” RAR-gamma 1 is important for normal skin maintenance and differentiation.
Ganoderma Lucidum extract and ganoderic acid A can help prevent hair loss.
October 2022 in “The Korean Journal of Physiology and Pharmacology” Targeting the PGD2-DP2 pathway may help treat hair loss.
7 citations
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March 2022 in “Scientific reports” Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.
6 citations
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January 2013 in “Genetics and Molecular Research” Women with hair loss have more androgen receptors in certain hair follicles.
8 citations
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April 2017 in “Journal of The Royal Society Interface” Giant axonal neuropathy changes the structure of keratin in human hair.
October 2025 in “Proceedings of the National Academy of Sciences” Phospholipids help plant proteins move by regulating receptor interactions.
April 2017 in “Journal of Investigative Dermatology” A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.
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September 2022 in “Molecular pharmacology” KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.
65 citations
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May 2001 in “Journal of Analytical Toxicology” Basic drugs like amphetamine are absorbed more in darker hair than lighter hair.
9 citations
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June 2017 in “Pharmacological Reports” ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.