60 citations
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December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
42 citations
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September 2002 in “The Journal of Comparative Neurology” Glycine likely affects dendrites connected to hair follicle terminals in rats.
40 citations
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December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
14 citations
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March 2017 in “Brain research” Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
1 citations
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April 2011 in “The FASEB Journal” Progesterone-derived neurosteroids affect GABA-A receptor expression, influencing epilepsy during menstrual cycles.
March 2008 in “The FASEB Journal” Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.
April 2008 in “Annals of General Psychiatry” Social isolation changes brain receptors and makes ethanol more impactful.
44 citations
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February 2009 in “Pain” Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
17 citations
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October 2012 in “European Journal of Pharmacology” Toluene lowers body temperature through different mechanisms depending on the concentration.
14 citations
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September 2017 in “Hormones and behavior” δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
11 citations
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January 2016 in “Molecular and Cellular Neuroscience” Chronic ethanol increases certain brain receptor levels, influenced by steroids and protein changes.
5 citations
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February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.
During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.
12 citations
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February 2017 in “Journal of neuroscience research” Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
15 citations
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June 2014 in “Behavioural Brain Research” Neurosteroids may help metyrapone reduce cocaine addiction.
October 2007 in “European Neuropsychopharmacology”
17 citations
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September 2013 in “The International Journal of Neuropsychopharmacology”
34 citations
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June 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
August 2008 in “European Neuropsychopharmacology” RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
44 citations
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September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
28 citations
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September 2002 in “The Journal of Comparative Neurology” Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
26 citations
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March 2006 in “Endocrine, metabolic & immune disorders. Drug targets” This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
17 citations
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October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
17 citations
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February 2009 in “Journal of Ethnopharmacology” Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
12 citations
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June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
11 citations
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December 2012 in “Alcoholism Clinical and Experimental Research” Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.
8 citations
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October 2019 in “The Journal of surgical research/Journal of surgical research” Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
7 citations
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October 2017 in “Behavioural Pharmacology” Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.