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Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.

Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Finasteride slows down motherly behavior in first-time pregnant rats.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.