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December 2010 in “Journal of Endocrinology” Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.
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April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.
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June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
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April 2017 in “Synapse” Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
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October 2015 in “Neurochemistry International” Letrozole may help prevent seizures by reducing certain hormone levels.
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July 2015 in “Frontiers in Cellular Neuroscience” Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.
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October 2002 in “Pharmacology Biochemistry and Behavior” Formalin-induced pain increases testosterone breakdown in the rat brain and spinal cord.
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February 2013 in “Neuroscience Letters” Allopregnanolone may help prevent nicotine withdrawal symptoms.
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