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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Sodium valproate helps skin healing by affecting GABA and histone deacetylase.

Cannabinoids may help treat various skin conditions.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Genetics influence opioid addiction risk, diet affects COVID-19 severity, Aerva lanata may harm kidneys, some plants fight fungi and cancer, and nursing students need better contraceptive knowledge.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride slows down motherly behavior in first-time pregnant rats.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

The mind and body don't directly interact; the mind acts as an interface linking abstract and physical data.

Ion channels play a key role in ovarian cancer growth and treatment resistance.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.