60 citations
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December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
January 2014 in “eScholarship (California Digital Library)” Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
19 citations
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September 2006 in “Journal of Neurophysiology” Neurosteroids help balance brain signals when certain inhibitions are reduced.
49 citations
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July 2008 in “Alcoholism Clinical and Experimental Research” Finasteride reduces alcohol consumption in mice by affecting brain chemicals.
35 citations
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May 2008 in “Drug and Alcohol Dependence” Female mice are less affected by certain substances that alter alcohol consumption compared to male mice.
12 citations
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December 2009 in “Neuroscience” GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
17 citations
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October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
28 citations
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September 2002 in “The Journal of Comparative Neurology” Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
12 citations
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September 2002 in “Journal of Neurochemistry” Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.
January 2012 in “ProQuest LLC eBooks” Changes in early neurosteroid levels can affect adult learning and anxiety.
27 citations
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April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
18 citations
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September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
44 citations
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October 2016 in “Epilepsia” 2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
16 citations
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October 2018 in “BMC Complementary and Alternative Medicine” Crataeva nurvala leaves may help reduce anxiety and improve sleep.
86 citations
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February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
25 citations
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July 2006 in “Journal of Neurochemistry” Progesterone affects GABAA receptor function by altering δ subunit levels.
During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.
9 citations
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January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
40 citations
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December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
137 citations
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
123 citations
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May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
61 citations
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January 2008 in “Biological & Pharmaceutical Bulletin” Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
20 citations
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November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
15 citations
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March 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
6 citations
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April 2015 in “Behavioural Brain Research” Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
2 citations
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September 2009 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
14 citations
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March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
110 citations
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August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
37 citations
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September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.