15 citations
,
November 2007 in “Journal of Neurochemistry” Stopping alcohol after long-term use causes anxiety and changes brain chemicals.
43 citations
,
December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
35 citations
,
April 2009 in “Journal of Neuroscience Research” HDAC inhibitors help brain cells grow and improve brain function.
11 citations
,
July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
1 citations
,
March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
33 citations
,
January 2008 in “Journal of Molecular Neuroscience” 26 citations
,
November 2013 in “Neuroscience” Progesterone can reduce seizures without relying on the GABAA receptor pathway.
6 citations
,
September 2023 in “Experimental physiology” A special receptor in sensory nerve endings helps control how they respond to stretching.
25 citations
,
November 2013 in “PLoS ONE” Estrogen and androgen signals control synaptic changes in rat brains.
28 citations
,
October 2011 in “British Journal of Pharmacology” Midazolam's seizure prevention is partly due to increased neurosteroid production.
January 2009 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Neurosteroids from glia cells help control seizure development in epilepsy.
66 citations
,
January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
11 citations
,
August 2014 in “PLoS ONE” GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
September 2002 in “Epiliepsy currents/Epilepsy currents” Stress increases neurosteroids that help prevent seizures.
80 citations
,
December 1996 in “Pain” Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
83 citations
,
November 2006 in “European Journal of Neuroscience” Progesterone protects rat brain cells by enhancing GABA A receptor activity.
49 citations
,
March 2012 in “Journal of Pharmacology and Experimental Therapeutics” Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” New ginseng compounds may help treat degenerative diseases.
11 citations
,
September 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
29 citations
,
October 2009 in “Pharmacology Biochemistry and Behavior”
2 citations
,
September 2009 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
16 citations
,
November 2018 in “Medicinal Chemistry” The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.
7 citations
,
June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” L. plantarum MTCC 1325 may help improve memory and cognitive functions in Alzheimer's.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Dopamine receptors in the brain influence itch-related scratching behavior.
65 citations
,
October 2008 in “Journal of Neuroendocrinology”
32 citations
,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
31 citations
,
January 2017 in “Phytotherapy Research” Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.