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Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.

A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.

CD28 is a promising target for treating alopecia areata with belatacept.

CD28 is a promising target for treating alopecia areata with belatacept.

BMP signaling is crucial for skin and hair growth.

Blocking certain immune signals can reduce skin damage from radiation therapy.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

The androgen receptor gene doesn't affect women with recurrent spontaneous abortions, but having a mutant genotype might protect against it.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.

RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.

Sphingosine 1-phosphate helps control mechanical pain.

DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.

Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

EGFR is crucial for preventing hair follicle inflammation and hair loss.

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Vitamin D receptor is essential for proper skin healing after injury.

Dlx3 is essential for hair growth and regeneration.

Immune activities and specific genes are important in male pattern baldness.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.