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Guselkumab effectively reduces fatigue in Psoriatic Arthritis patients over two years.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

GIANT improves brain imaging by using genetics to better map brain regions.

New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.

Targeting METTL1 may help slow papillary thyroid cancer growth and spread.

Early diagnosis and treatment are crucial for managing Berardinelli–Seip syndrome.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Agalsidase alfa helps treat Fabry's disease but needs more research for long-term benefits.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

The HSD3B1 variant increases hair loss risk in overweight women with PCOS.

The document concludes that measuring γ-glutamyl transpeptidase activity is more accurate with a higher substrate concentration and using diluted acetic acid to stop the reaction.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Mutations in the Sgk3 gene cause fuzzy hair in mice.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.

Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.

A special receptor in sensory nerve endings helps control how they respond to stretching.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

STEAP3 protein might help treat hair loss, but more testing is needed.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

The AR gene is linked to male-pattern baldness, TNFSF4 to heart disease, SLC19A3 to BBGD, MCT8 to a syndrome, and segmental duplications to genetic variation.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

A defective gene causes hair loss and taste insensitivity in BTBR mice.

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

BTNL2 helps protect hair follicles from immune attacks, which could aid in treating alopecia areata.

TEDAR is crucial for skin cell differentiation and barrier formation.