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Personalized sonidegib dosing can effectively treat Gorlin-Goltz syndrome with fewer side effects.

Transgender and gender diverse youth often have skin issues like acne and scarring, but few get referred to dermatologists.

A new method can quickly and accurately detect drugs in hair.

Recombinant human TSG-6 speeds up wound healing in diabetic mice.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Gambogic Amide may prevent hair greying and promote hair growth by maintaining hair pigmentation.

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

Direct-to-consumer teledermatology effectively treats male hair loss but may increase drug costs and requires monitoring for side effects.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

Normal skin results from interactions between EGF and the Tabby mutation.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Disitamab vedotin and gemcitabine effectively treated bladder cancer without major side effects.

The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.

HGF combined with ADA is highly accurate for diagnosing tuberculous pleural effusion, especially in younger females.

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Gap junctions help control feather pattern formation in chickens.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

Routine genetic testing is crucial for early diagnosis and better management of Turner’s syndrome with 21-hydroxylase deficiency.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.

Autologous growth factor concentrate therapy shows promise for treating early-stage hair loss safely and effectively.

Toxoplasma gondii infection may increase testosterone levels in males.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.