October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology” A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.
3 citations
,
June 2015 in “Serbian Journal of Dermatology and Venereology” The conclusion is that cerebrovascular diseases can cause seizure-like activity in stroke patients, which can be improved with antiepileptic drugs.
60 citations
,
December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
38 citations
,
November 2005 in “Epilepsia” Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
January 2008 in “Elsevier eBooks” The young woman with epilepsy became seizure-free after finding the right combination of medications.
12 citations
,
February 2017 in “Journal of neuroscience research” Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
4 citations
,
May 1994 in “Neurology” The boy had a unique condition with seizures, uneven hair loss, and an enlarged brain hemisphere.
February 2009 in “Mayo Clinic proceedings” A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
October 2010 in “Epilepsy Currents” Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
44 citations
,
October 2016 in “Epilepsia” 2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
59 citations
,
October 1976 in “Acta Neurologica Scandinavica” Sodium valproate reduced seizures in many patients with resistant epilepsy.
Sodium valproate improved epilepsy control in most children but often caused weight gain and other mild side effects.
44 citations
,
December 1975 in “Developmental Medicine & Child Neurology” Sodium valproate effectively controls petit mal seizures in children but is less effective for other types, with minimal side effects.
Levetiracetam and valproate sodium both reduce seizures when added to lamotrigine, but levetiracetam has fewer side effects.
3 citations
,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
January 2025 in “Seizure” Dual anti-seizure medications, especially valproic acid with lamotrigine, often cause more side effects like hair loss and memory issues.
20 citations
,
January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
170 citations
,
June 1974 in “BMJ” Sodium valproate effectively reduces seizures in epilepsy, especially in absences and myoclonic types, with minimal side effects.
294 citations
,
February 1994 in “PubMed” Valproic acid is an effective and safe first-choice treatment for many types of seizures.
January 2009 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Neurosteroids from glia cells help control seizure development in epilepsy.
1 citations
,
January 2018 in “Journal of Neurology Research” A young man had rare serious side effects from an epilepsy drug, leading to stopping the drug.
8 citations
,
February 2003 in “Annals of Neurology” Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
30 citations
,
February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
49 citations
,
March 2012 in “Journal of Pharmacology and Experimental Therapeutics” Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
12 citations
,
May 2005 in “Journal of the American Geriatrics Society” Stopping valproate and using lactulose can quickly treat valproate-induced hyperammonemia.
24 citations
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November 1978 in “JAMA” Valproic acid is effective for various seizures, but may cause temporary side effects like drowsiness and stomach issues.
January 2024 in “Wiadomości Lekarskie” Effective epilepsy management involves accurate diagnosis, understanding seizure types, identifying causes, and choosing the right treatment.
40 citations
,
December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
5 citations
,
January 2017 in “Nevrologiâ, nejropsihiatriâ, psihosomatika” Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.
17 citations
,
January 2013 in “Indian Journal of Pharmacology” High levels of the seizure medication sodium valproate can cause hair loss.