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research Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation

71 citations , November 2012 in “Expert Opinion on Drug Safety”

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors

66 citations , December 2014 in “Nature Communications”

Fibroblasts can be turned into melanocytes for potential skin treatments.

research Edible seeds from Cucurbitaceae family as potential functional foods: Immense promises, few concerns

54 citations , May 2017 in “Biomedicine & Pharmacotherapy”

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

research Spatiotemporal control of CRISPR/Cas9 gene editing

51 citations , June 2021 in “Signal Transduction and Targeted Therapy”

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

research Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women

39 citations , September 2012 in “Human Reproduction”

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis

38 citations , June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research The Effect of 5 -Reductase Inhibitors on Erectile Function

31 citations , September 2008 in “International Journal of Andrology”

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

research Characteristics of flutamide action on prostatic and testicular functions in the rat

30 citations , June 1988 in “Journal of Steroid Biochemistry”

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

research Cloning of the human phenol sulfotransferase gene family: three genes implicated in the metabolism of catecholamines, thyroid hormones and drugs

26 citations , February 1998 in “Chemico-Biological Interactions”

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

research Effects of Oral Finasteride on Erectile Function in a Rat Model

25 citations , February 2012 in “The Journal of Sexual Medicine”

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

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