77 citations
,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
76 citations
,
November 2010 in “Journal of The American Academy of Dermatology” Some African American women's central scalp hair loss is linked to genetics and past fungal scalp infections, with more research needed on other causes.
62 citations
,
January 2010 in “Hormone research in paediatrics” Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
62 citations
,
March 2008 in “American Journal of Human Genetics” Hair loss gene found on chromosome 3q26.
59 citations
,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
53 citations
,
September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
41 citations
,
October 2011 in “Clinical and Experimental Dermatology” G allele of AR Stul polymorphism linked to higher hair loss risk, especially in white people.
35 citations
,
May 1986 in “Clinics in endocrinology and metabolism” The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
31 citations
,
January 2010 in “GenomeBiology.com (London. Print)” The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
30 citations
,
December 2014 in “BMC Genetics” Certain genes and proteins may influence wool growth in Aohan fine wool sheep.
29 citations
,
November 2022 in “Nature Medicine” Genetic variations greatly affect individual metabolism and can impact health and disease risk.
29 citations
,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
27 citations
,
December 2015 in “Mayo Clinic Proceedings” The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
23 citations
,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
19 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” Children's hairlines change shape as they grow, with women often developing a widow's peak and men's hairlines becoming more convex and possibly balding at the temples, influenced by genetics and hormones.
19 citations
,
December 2015 in “European Journal of Human Genetics” A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
18 citations
,
April 2013 in “Inflammatory Bowel Diseases” People with Inflammatory Bowel Disease often lose hair due to stress, medication side effects, or lack of nutrients, and treatment depends on the specific cause.
18 citations
,
February 2006 in “Genomics” A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
18 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin patterns are formed by simple reaction-diffusion mechanisms.
16 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
15 citations
,
November 2015 in “Trends in biotechnology” Gene regulation could revolutionize hair color by altering pigmentation from within.
14 citations
,
August 2021 in “Molecular Genetics and Metabolism Reports” Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
12 citations
,
June 2021 in “Scientific Reports” Curcumin may help reverse aging by targeting specific genes.
11 citations
,
January 2020 in “BMC pediatrics” New mutations in the SLC39A4 gene found in twins help understand the genetic cause of acrodermatitis enteropathica.
8 citations
,
October 2019 in “Immunological investigations” The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.
8 citations
,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
7 citations
,
February 2019 in “International Journal of Dermatology” Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
7 citations
,
January 2013 in “Journal of Investigative Dermatology” Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.