August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
38 citations
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June 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
13 citations
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July 2019 in “Journal of Dermatological Science” Increasing alkaline phosphatase in human skin cells helps to grow more hair.
28 citations
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January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
209 citations
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September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
98 citations
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February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
57 citations
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May 2007 in “Nature” Adult mice can grow new hair from skin wounds.
34 citations
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April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
16 citations
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March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
81 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
12 citations
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January 2021 in “International Journal of Biological Sciences” Scientists successfully edited a goat's genes to grow more and longer cashmere hair.
10 citations
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July 2019 in “Advances in Wound Care” Reducing Flightless I protein improves wound healing by activating skin stem cells.
April 2023 in “Medizinische Genetik” New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
65 citations
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March 2004 in “Journal of Clinical Investigation” Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
3 citations
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July 2025 in “Gels” Engineered protein hydrogels improve medical treatments by mimicking natural body structures.
January 2014 in “American Journal of Medicine and Medical Sciences” Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.
160 citations
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June 2008 in “American Journal Of Pathology” EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.
64 citations
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March 2004 in “Journal of Clinical Investigation” Targeting ornithine decarboxylase can help prevent skin cancer.
62 citations
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October 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes can change hair structure and cause monilethrix, with nail issues more common in certain gene mutations.
6 citations
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May 2020 in “Nutrients” Eating fewer calories may slow skin aging and improve skin health through various biological changes.
January 2025 in “Research” Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
70 citations
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March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
829 citations
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May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
180 citations
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September 1999 in “British Journal of Dermatology” Hair loss affects self-esteem and quality of life; treatments can help.
138 citations
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March 2001 in “Clinics in Dermatology” Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.
102 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
70 citations
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January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.